宇文力辉，信息材料与纳米技术研究院/材料科学与工程学院副教授，硕士生导师
联系方式：
办公地点：南京邮电大学仙林校区教五-211
Email：iamlhyuwen@njupt.edu.cn
个人简历
2001/09 - 2005/06，兰州大学，材料化学，学士
2005/09 - 2011/06，复旦大学，高分子化学与物理，博士
2011/07 - 至今，南京邮电大学，教师
2017/07 - 2018/02，新加坡南洋理工大学，访问学者
研究方向
[1] 金属硫族化合物纳米材料的可控制备、表面功能化及其生物传感应用。
[2] 环境响应型智能纳米试剂的设计、构建及其在重大疾病诊疗中的应用。
研究项目
[1] 江苏省自然科学基金面上项目（BK20191382），微环境响应-调控型二维纳米材料的制备及其对细菌生物膜感染的协同治疗，2019年7月-2022年6月，10万，主持，结题；
[2] 国家自然科学基金青年基金项目（51503101），基于交联增强自组装策略构建高稳定性量子点荧光探针及其在肺癌miRNA标志物检测中的应用，2016年1月-2018年12月，25.05万，主持，结题；
[3] 江苏省自然科学基金青年基金项目（BK20130862），高性能量子点生物探针的纳米生物界面可控构建及其在肝癌标志物检测中的应用，2013年7月-2016年7月，20万，主持，结题；
学术成果
研究领域为纳米生物医学，重点围绕智能响应型纳米生物材料的设计、构建及疾病诊断与治疗开展了一系列研究工作。近年来在Science Advances、Nature Communications、ACS Nano、Research、Materials Horizons、VIEW、Small等学术刊物发表SCI论文60余篇，成果得到Advanced Science News、MaterialsViews、科技日报等专题报道，研究成果获得江苏省科学技术奖二等奖和中国电子学会科学技术奖二等奖。
代表性论文
[1] Weijun Xiu, Lili Ren, Huayu Xiao, Yue Zhang, Dou Wang, Kaili Yang, Siyu Wang, Lihui Yuwen*, Xiao Li, Heng Dong, Qiang Li, Yongbin Mou, Yuqian Zhang, Zhaowei Yin, Bin Liang, Yu Gao*, Lianhui Wang*, Ultrasound-responsive catalytic microbubbles enhance biofilm elimination and immune activation to treat chronic lung infections. Science Advances, 2023, 9, eade5446.
[2] Heng Dong#, Weijun Xiu#, Ling Wan, Qiang Li, Yu Zhang, Meng Ding, Jingyang Shan, Kaili Yang, Zhaogang Teng*, Lihui Yuwen*, Yongbin Mou*, Biofilm microenvironment response nanoplatform synergistically degrades biofilm structure and relieves hypoxia for efficient sonodynamic therapy. Chemical Engineering Journal, 2023, 453, 139839.
[3] Lihui Yuwen, Huayu Xiao, Pei Lu, Xiaolong Chen, Jianguang Li, Weijun Xiu, Siyu Gan, Dongliang Yang, Lianhui Wang, Amylase degradation enhanced NIR photothermal therapy and fluorescence imaging of bacterial biofilm infections. Biomaterials Science, 2023, 11, 630-640.
[4] Weijun Xiu, Ling Wan, Kaili Yang, Xiao Li, Lihui Yuwen*, Heng Dong, Yongbin Mou, Dongliang Yang, Lianhui Wang*, Potentiating hypoxic microenvironment for antibiotic activation by photodynamic therapy to combat bacterial biofilm infections. Nature Communications, 2022, 13, 3875.
[5] Yanling Hu, Hui Li, Xinyi Lv, Yan Xu, Yannan Xie, Lihui Yuwen*, Yingnan Song, Shengke Li*, Jinjun Shao, Dongliang Yang*, Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds. Nanoscale, 2022, 14, 12967-12983.
[6] Weijun Xiu, Jingyang Shan, Kaili Yang, Hang Xiao, Lihui Yuwen*, Lianhui Wang*, Recent development of nanomedicine for the treatment of bacterial biofilm infections. VIEW, 2021, 2, 20200065.
[7] Yuqing Li, Weijun Xiu, Kaili Yang, Qirui Wen, Lihui Yuwen*, Zichao Luo, Xiaogang Liu, Dongliang Yang, Xiaoji Xie, Lianhui Wang*, A multifunctional Fenton nanoagent for microenvironment-selective anti-biofilm and anti-inflammatory therapy. Materials Horizons, 2021, 8, 1264-1271.
[8] Weijun Xiu, Siyu Gan, Qirui Wen, Qiu Qiu, Sulai Dai, Heng Dong, Qiang Li, Lihui Yuwen*, Lixing Weng, Zhaogang Teng, Yongbin Mou, Lianhui Wang*, Biofilm Microenvironment-Responsive Nanotheranostics for Dual-Mode Imaging and Hypoxia-Relief-Enhanced Photodynamic Therapy of Bacterial Infections. Research, 2020, 9426453.
[9] Jingyang Shan, Kaili Yang, Weijun Xiu, Qiu Qiu, Sulai Dai, Lihui Yuwen*, Lixing Weng, Zhaogang Teng, Lianhui Wang*, Cu2MoS4 Nanozyme with NIR-II Light Enhanced Catalytic Activity for Efficient Eradication of Multidrug-Resistant Bacteria. Small, 2020, 16, 2001099.
[10] Jingyang Shan, Xiao Li, Kaili Yang, Weijun Xiu, Qirui Wen, Yuqian Zhang, Lihui Yuwen*, Lixing Weng, Zhaogang Teng, Lianhui Wang*, Efficient Bacteria Killing by Cu2WS4 Nanocrystals with Enzyme-like Properties and Bacteria-Binding Ability. ACS Nano, 2019, 13, 13797-13808.