沈清明

时间:2017-11-27   浏览:13728

  


沈清明,男,博士,教授,博士生导师

江苏省“333高层次人才培养工程”中青年学术技术带头人

实验室建设与管理处处长


联系方式:

办公地点:南京市文苑路9南京邮电大学教五-421

Emailiamqmshen@njupt.edu.cn

电话:+86-25-85866827

个人简历:

2016.09-                南京邮电大学材料科学与工程学院           教授

2015.03-2016.05  美国佛罗里达大学生物医学工程系            访问学者

2010.11-2016.08   南京邮电大学材料科学与工程学院            副教授

2008.12-2010.11   南京大学化学化工学院                                博士后

2005.09-2008.11   南京大学化学化工学院                                博士

2002.09-2005.07   河南师范大学化学与环境科学学院            硕士

1998.09-2002.07   河南师范大学化学与环境科学学院            学士

研究方向:

研究方向为光电纳米材料(金属、半导体及有机/无机杂化纳米材料等)的合成、光电器件的制备、生物传感与成像等。

具体包括:

1. 制备了多种新型光电纳米材料及其复合物;

2. 构建了多种高灵敏纳米光电化学生物传感器;

3. 开发了多种可控激活型活体肿瘤纳米诊疗体系。

人才培养:

承担本科生《材料分析技术》、《材料化学导论》和《高分子化学实验》以及研究生《现代分析技术》的教学工作。

奖励与荣誉:

合成一系列性能优异的新型光电纳米材料,发展了基于新型纳米材料的光电化学生物传感器及其诊疗技术。在Adv. Funct. Mater.,Biomaterials, Small, Anal. Chem., Chem. Commu., Biosens. & Bioelectron.等知名学术期刊上发表60余篇SCI论文SCI文章他引3000余次。

主要研究项目:

1. 基于硫化铋纳米体系的多模态分子影像探针及其肿瘤靶向诊疗(21575069)国家自然科学基金面上项目主持

2.  半导体纳米材料光电生物传感研究(21105050),国家自然科学基金青年基金  主持

3.  多重响应型近红外二区荧光诊疗探针(20KJA430012),江苏省高校自然科学基金重大项目主持

4.  光控激活型DNA分子NIR-II荧光探针的制备及其肿瘤microRNA成像分析应用BK20221326),江苏省基础研究计划面上项目主持

5.  新工科视域下材料类专业创新创业能力培养的研究与实践(2021JSJG592),江苏省高等教育教改研究立项课题重点项目主持

6. 半导体纳米材料合成及其光电生物传感应用(20113223120004),高等学校博士学科点专项科研基金联合资助课题主持

7.  纳米Bi2S3光声/光热探针及其肿瘤诊疗(14KJB150015),江苏省高校自然科学基金主持

8.  石墨烯/半导体纳米复合材料的合成及其光电应用(11KJB150011),江苏省高校自然科学基金主持

代表性著作:

1.  Yeneng Dai, Fan Zhang, Kai Chen, Zhiquan Sun, Zhihang Wang, Yuwen Xue, Meixing Li, Quli Fan, Qingming Shen*, Qi Zhao*, An Activatable Phototheranostic Nanoplatform for TumorSpecific NIR-II Fluorescence Imaging and Synergistic NIR-II Photothermal-Chemodynamic Therapy, Small, 2023, 19, 2206053.

2.  Dashan Qi, Haowei Zhu, Yingjie Kong and Qingming Shen*, Injectable Nanomedicine–Hydrogel for NIR Light Photothermal–Chemo Combination Therapy of Tumor, Polymers,2022, 14, 5547.

3.   Meixing Li,* Ziyi Yuan, Lei Zhang, Huiyu Zhou, Qingming Shen*, Dual-Potential Ratiometric Electrochemiluminescence Microrna Bioassay Based on Inner Reference Probe and Catalytic Hairpin Assembly, Sensors & Actuators: B. Chemical, 2022, 373, 132747.

4. Chen Yang, Wenli Jiang, Yongqi Yu, Hui Zhang*, Chenxin Cai, Qingming Shen*, Anisotropic Plasmonic Pd-Tipped Au Nanorods for Near-Infrared Light-Activated Photoacoustic Imaging Guided Photothermal-Photodynamic Cancer Therapy, Journal of Materials Chemistry B, 2022, 10, 2028.

5.  Yeneng Dai, Wenyu Du, Diya Gao, Haowei Zhu, Fan Zhang, Kai Chen, Haiyang Ni,   Meixing Li, Quli Fan, Qingming Shen*, Near-infrared-II Light Excitation Thermosensitive Liposomes for Photoacoustic Imaging Guided and Enhanced Photothermal-Chemo Synergistic Tumor Therapy, Biomaterials Science, 2022, 10, 435.

6.  Yeneng Dai, Honghai Zhao, Kun He, Wenyu Du, Yingjie Kong, Zhen Wang, Meixing Li, Qingming Shen*, Pengfei Sun*, Quli Fan*, NIR-II Excitation Phototheranostic Nanomedicine for Fluorescence/Photoacoustic Tumor Imaging and Targeted Photothermal-Photonic Thermodynamic Therapy, Small, 2021, 17, 2102527.

7.   Yeneng Dai, Zhiquan Sun, Honghai Zhao, Dashan Qi, Xiangyu Li, Diya Gao, Meixing Li, Quli Fan, Qingming Shen*, Wei Huang*, NIR-II Fluorescence Imaging Guided Tumor-Specific NIR-II Photothermal Therapy Enhanced by Starvation Mediated Thermal Sensitization Strategy, Biomaterials, 2021, 275, 120935.

8.  Meixing Li*, Juan Cheng, Ziyi Yuan, Huiyu Zhou, Lei Zhang, Yeneng Dai, Qingming Shen*, Quli Fan, Sensitive electrochemical detection of microRNA based on DNA walkers and hyperbranched HCR-DNAzyme cascade signal amplification strategy, Sensors & Actuators: B. Chemical, 2021, 345, 130348.

9.  Meixing Li*, Juan Cheng, Ziyi Yuan, Qingming Shen*, Quli Fan, DNAzyme-Catalyzed Etching Process of Au/Ag Nanocages Visualized via Dark-Field Imaging with Time Elapse for Ultrasensitive Detection of MicroRNA, Sensors & Actuators: B. Chemical, 2021, 330, 129347.

10.   Bing Wang, Yeneng Dai, Yingjie Kong, Wenyu Du, Haiyang Ni, Honghai Zhao, Zhiquan Sun, Qingming Shen*, Meixing Li*, Quli Fan*, Tumor Microenvironment-Responsive Fe(III)−Porphyrin Nanotheranostics for Tumor Imaging and Targeted Chemodynamic−Photodynamic Therapy, ACS Appl. Mater. Interfaces, 2020, 12, 53634.

11.   Jian-Hua Qin, Hua Zhang, Pengfei Sun*, Ya-Dan Huang, Qingming Shen*, Xiao-Gang Yang, Lu-Fang Ma*, Ionic Liquid Induced Highly Dense Assembly of Porphyrin in MOF Nanosheets for Photodynamic Therapy, Dalton Trans., 2020, 49, 17772.

12.  Qi Wang, Yeneng Dai, Jingzeng Xu, Jie Cai, Xinrui Niu, Lei Zhang, Runfeng Chen, Qingming Shen*, Wei Huang, Quli Fan*, All-in-One Phototheranostics: Single Laser Triggers NIR-II Fluorescence/Photoacoustic Imaging Guided Photothermal/Photodynamic/Chemo Combination Therapy, Adv. Funct. Mater., 2019, 1901480.

13.  Yeneng Dai, Bing Wang, Zhiquan Sun, Juan Cheng, Honghai Zhao, Kun Wu, Pengfei Sun, Qingming Shen*, Meixing Li*, Quli Fan*, Multifunctional Theranostic Liposomes Loaded with a Hypoxia-Activated Prodrug for Cascade-Activated Tumor Selective Combination Therapy, ACS Appl. Mater. Interfaces, 2019, 11, 39410.

14.  Kun Wu, Honghai Zhao, Zhiquan Sun, Bing Wang, Xueying Tang, Yeneng Dai, Meixing Li, Qingming Shen*, Hui Zhang*, Quli Fan*, Wei Huang, Endogenous Oxygen Generating Multifunctional Theranostic Nanoplatform for Enhanced Photodynamic-Photothermal Therapy and Multimodal Imaging, Theranostics, 2019, 9, 7697.

15.   Yeneng Dai, Jinzhong Su, Kun Wu, Wenkang Ma, Bing Wang, Meixing Li, Pengfei Sun, Qingming Shen*, Qi Wang*, Quli Fan*, Multifunctional Thermosensitive Liposomes Based on Natural Phase-Change Material: Near-Infrared Light-Triggered Drug Release and Multimodal Imaging-Guided Cancer Combination Therapy, ACS Appl. Mater. Interfaces, 2019, 11, 10540.

授权专利:

1.  沈清明,樊晓慧,范曲立,黄维;一种硫化铋纳米球的室温水相制备方法, ZL201510189099.9.

2.  沈清明,樊晓慧,范曲立,黄维;一种硫化铋/蛋白质复合纳米球的水相制备方法,ZL201510189186.4.

3. 沈清明,刘石磊,范曲立,黄维;一种贵金属/二氧化钛纳米复合物的制备方法,ZL201510188503.0.

4. 沈清明,戴叶能,苏金中,范曲立;一种脂质体制备方法,ZL201811464832.3.

5. 沈清明,苏金中,戴叶能,赵红海,范曲立;一种Au@Se@Pt-Ce6纳米复合探针及其制备方法,ZL201910337566.6.

6. 沈清明,戴叶能,王兵,孙志权,范曲立;一种共轭钆的FA-CuS/Ce6-Gd纳米诊疗探针及其制备方法与应用,ZL201910370785.4.

7. 沈清明,戴叶能,王兵,孙志权,赵红海,范曲立;一种近红外光激活的多功能脂质体及其制备方法与应用,ZL201910370871.5.

8. 沈清明,马文康,赵红海,孙志权,范曲立;一种铂@聚多巴胺-二氢卟吩纳米复合材料及其制备方法和应用,ZL201910337656.5.

9. 沈清明,唐雪莹,李美星,范曲立;一种基于阴极光电极构建的光电生物传感器,ZL202010497179.1.

10. 沈清明,孙志权,杜文宇,倪海洋,范曲立;一种多功能抗肿瘤纳米药物及其制备方法和应用,ZL202110539011.7.